Case Study
August 10, 2023
5min
High Performance Computing using Parallel Cluster, Infrastructure Set-up
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Iridescent Bio is headquartered in Leiden, The Netherlands, and focuses on using physicochemical modeling and AI to predict developability for antibody R&D in biopharma. Their cloud tool, Spectiv, can reverse-engineer antibody patents to extract a developability profile, or predict this when prototyping new sequences. In the 21st century, Biology is increasingly intertwined with Data, the Cloud, AI, and modeling, creating a symbiotic relationship. Biomolecules have become essential foundations for potent therapies. The importance of patenting and intellectual property (IP) in the field of biopharmaceuticals is set to multiply exponentially. The vision of Iridescent Bio is to provide the premium platform for unraveling, modeling, analyzing, and forecasting intellectual property (IP) in protein-based pharmaceutical sciences, encompassing every level from atomic structure to practical application and empower researchers and businesses to expedite the introduction of groundbreaking therapies to the market, catalyzing the transformation of biotechnology and generating wide-ranging benefits for society.
Iridescent Bio has developed a web application where users can enter a biopharma patent number or antibody (protein) sequence . This will ignite the generation of 3D data for each sequence and perform complex calculations to generate reports and send them back to the end user. For performing complex calculations they needed a high performance computing infrastructure which is robust, stable, highly available and scalable with automated deployment and termination aspects. The Iridescent Bio team was looking for a partner who can build and manage their infrastructure on AWS. Iridescent Bio wanted to establish an end-to-end streamlined process for the end-users. The user can input a patent number or antibody sequence seamlessly through a user-friendly web interface, triggering a series of calculations and operations in the cloud. Once the processing is complete, a comprehensive report has to be generated and securely delivered to the customer. A top priority was also to ensure the utmost security by implementing robust measures to protect the data, as well as considering all necessary security parameters for data, application hosting, and high-performance computing (HPC) infrastructure. The deployment of GPU and CPU intensive models, which require significant core hours to complete simulations, has to be facilitated on a single, secured platform. Ankercloud actively supported Iridescent Bio in designing and implementing the appropriate solution on AWS which includes components such as virtual machines, storage, and networking to optimize resource utilization. Additionally, upon completion of the processing, all data, calculations and the underlying cluster will be systematically destroyed, guaranteeing complete data privacy and security.
Setting up an HPC cluster in AWS Environment for completing the desired task automatically without any human intervention.
For each patent ID or antibody sequence a separate HPC environment will be created.
Deleting the resources created post completion of the task.
Overall, the business outcomes achieved through the high-performance cluster solution and reduced computing time have positively impacted the client's productivity, user experience, and competitive positioning. The improved efficiency and throughput have set the stage for further growth and innovation in the client's domain with enhanced security along with cost effectiveness.
Based on the joint project and AWS set-up the Iridescent Bio team was able to launch their platform for their customers. Are you interested to see this project in action? take a look at: https://spectiv.bio/
Ankercloud has been delivering projects utilizing AWS services & helping clients across the globe. Ankercloud is an advanced partner for AWS with a long experience of delivering solutions on multi-cloud platforms. A team of professionals closely discuss the requirements & architect the solution approach in an agile model of project delivery. A hands-on consulting approach is encouraged at all levels within the organization to gain the customers’ trust and respect. This provides Ankercloud with a competitive edge in the partner ecosystem as a preferred choice.
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